The place is spotlessly clean, very comfortable, with a good bed, and all sorts of little touches to make the stay nice. There is a free computer with internet for use. The service is wonderful with no help being too much (from information to umbrellas for a rainy day, to early breakfasts, and chocolates in your room!), while not being too much or obtrusive. It is a very quiet location within literally 1 block from Vatican, and several busses and metro to the center.
We were so close to Vatican, that we passed the St. Pieter's square at least a couple of times a day on our way to the city! We walked to the center and Trastevere (15-40 min walk, depending on the location). Also being so close to Vatican made it easy to be there early to avoid the huge crows for the Vatican museum.
We would definetely stay there again, and can't wait for our next visit to Rome, which is overwhelming.